Abstract Background Colistin is a polymyxin antibiotic which has been used for treatment of Gram-negative infections. but it was withdrawn due to its nephrotoxicity. However. colistin has gained its popularity in recent years due to the reemergence of multidrug resistant Gram-negative infections and drug-induced toxicity is considered as the main obstacle for using this valuable antib... https://parisnaturalfoodes.shop/product-category/sleep-tight-melatonin/