COVID-19-infected patients require an intact immune system to suppress viral replication and prevent complications. However. the complications of SARS-CoV-2 infection that led to death were linked to the overproduction of proinflammatory cytokines known as cytokine storm syndrome. This article reported the various checkpoints targeted to manage the SARS-CoV-2-induced cytokine storm. https://megavitamines.shop/product-category/caffeine/