ObjectiveAcetylcholine modulates the activity of the direct and indirect pathways within the striatum through interaction with muscarinic M4 and M1 receptors. M4 receptors are uniquely positioned to regulate plasticity within the direct pathway and play a substantial role in reward and addiction-related behaviors. However. the role of M4 receptors on cholinergic neurons has been less ... https://unitedssports.shop/product-category/lacrosse-sticks-complete/